For many years I have studied the implications of innovation activities for firm strategies, market structure, and economic growth more generally. Given the uncertainty surrounding innovation decisions, both in firms and economies, I have recently become interested in how firms and entrepreneurs can make better decisions under uncertainty. Through a series of randomized control trials, conducted with Arnaldo Camuffo and other colleagues, we have demonstrated that decision-makers employing a scientific approach (theory and tests) make better decisions. The ION Management Science Lab at SDA Bocconi has taken up this stream of research with the aim at providing micro-foundation for management and strategy, particularly in the context of the ongoing digital revolution. The Lab also focuses on how to make our scientific understanding of strategic decision-making processes practical and useful to managers and entrepreneurs to make their decisions.